Novel Immunotherapeutic Strategies of Gastric Cancer Treatment
Joint Authors
Amedei, Amedeo
D'Elios, Mario M.
della Bella, Chiara
Benagiano, Marisa
Niccolai, Elena
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-27
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Gastric cancer (GC) is the fourth most common cancer and the second most frequent cause of cancer-related deaths, accounting for 10.4% of cancer deaths worldwide.
Despite the improvements, estimated cure rates for patients with advanced stages remain poor, and in the metastatic setting, chemotherapy is the mainstay of palliative therapy and results in objective response rates (ORRs) of only 20–40% and median overall survivals (OS) of 8–10 months.
Therefore, many investigators believe that the potential for making significant progress lies in understanding and exploiting the molecular biology of these tumors to investigate new therapeutic strategies to combat GC, such as specific immunotherapy.
In this paper, we analyze the different approaches used for immune-based (especially dendritic and T cells) therapies to gastric cancer treatment and discuss the results obtained in preclinical models as in clinical trials.
American Psychological Association (APA)
Amedei, Amedeo& Benagiano, Marisa& della Bella, Chiara& Niccolai, Elena& D'Elios, Mario M.. 2011. Novel Immunotherapeutic Strategies of Gastric Cancer Treatment. BioMed Research International،Vol. 2011, no. 2011, pp.1-17.
https://search.emarefa.net/detail/BIM-990096
Modern Language Association (MLA)
Amedei, Amedeo…[et al.]. Novel Immunotherapeutic Strategies of Gastric Cancer Treatment. BioMed Research International No. 2011 (2011), pp.1-17.
https://search.emarefa.net/detail/BIM-990096
American Medical Association (AMA)
Amedei, Amedeo& Benagiano, Marisa& della Bella, Chiara& Niccolai, Elena& D'Elios, Mario M.. Novel Immunotherapeutic Strategies of Gastric Cancer Treatment. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-17.
https://search.emarefa.net/detail/BIM-990096
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990096