Emerging Functions of Transcription Factors in Malaria Parasite
Joint Authors
Tuteja, Renu
Ansari, Abulaish
Chauhan, Virander Singh
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Transcription is a process by which the genetic information stored in DNA is converted into mRNA by enzymes known as RNA polymerase.
Bacteria use only one RNA polymerase to transcribe all of its genes while eukaryotes contain three RNA polymerases to transcribe the variety of eukaryotic genes.
RNA polymerase also requires other factors/proteins to produce the transcript.
These factors generally termed as transcription factors (TFs) are either associated directly with RNA polymerase or add in building the actual transcription apparatus.
TFs are the most common tools that our cells use to control gene expression.
Plasmodium falciparum is responsible for causing the most lethal form of malaria in humans.
It shows most of its characteristics common to eukaryotic transcription but it is assumed that mechanisms of transcriptional control in P.
falciparum somehow differ from those of other eukaryotes.
In this article we describe the studies on the main TFs such as myb protein, high mobility group protein and ApiA2 family proteins from malaria parasite.
These studies show that these TFs are slowly emerging to have defined roles in the regulation of gene expression in the parasite.
American Psychological Association (APA)
Tuteja, Renu& Ansari, Abulaish& Chauhan, Virander Singh. 2011. Emerging Functions of Transcription Factors in Malaria Parasite. BioMed Research International،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-990111
Modern Language Association (MLA)
Tuteja, Renu…[et al.]. Emerging Functions of Transcription Factors in Malaria Parasite. BioMed Research International No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-990111
American Medical Association (AMA)
Tuteja, Renu& Ansari, Abulaish& Chauhan, Virander Singh. Emerging Functions of Transcription Factors in Malaria Parasite. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-990111
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990111