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Regulatory T Cells and Parasites
Joint Authors
Velavan, TP.
Ojurongbe, Olusola
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Human host encounters a wide array of parasites; however, the crucial aspect is the failure of the host immune system to clear these parasites despite antigen recognition.
In the recent past, a new immunological concept has emerged, which provides a framework to better understand several aspects of host susceptibility to parasitic infection.
It is widely believed that parasites are able to modulate the magnitude of effector responses by inducing regulatory T cell (Tregs) population and several studies have investigated whether this cell population plays a role in balancing protective immunity and pathogenesis during parasite infection.
This review discusses the several mechanism of Treg-mediated immunosuppression in the human host and focuses on the functional role of Tregs and regulatory gene polymorphisms in infectious diseases.
American Psychological Association (APA)
Velavan, TP.& Ojurongbe, Olusola. 2011. Regulatory T Cells and Parasites. BioMed Research International،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-990172
Modern Language Association (MLA)
Velavan, TP.& Ojurongbe, Olusola. Regulatory T Cells and Parasites. BioMed Research International No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-990172
American Medical Association (AMA)
Velavan, TP.& Ojurongbe, Olusola. Regulatory T Cells and Parasites. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-990172
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990172