Safety and Clinical Usage of Newcastle Disease Virus in Cancer Therapy
Joint Authors
Alitheen, Noorjahan Banu Mohamed
Rasoli, Mehdi
Omar, Abdul Rahman
Lam, Han Yuen
Yusoff, Khatijah
Abdul Aziz, Suraini
Yeap, Swee Keong
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-26
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Newcastle disease virus (NDV) is an avian virus that causes deadly infection to over 250 species of birds, including domestic and wild-type, thus resulting in substantial losses to the poultry industry worldwide.
Many reports have demonstrated the oncolytic effect of NDV towards human tumor cells.
The interesting aspect of NDV is its ability to selectively replicate in cancer cells.
Some of the studies have undergone human clinical trials, and favorable results were obtained.
Therefore, NDV strains can be the potential therapeutic agent in cancer therapy.
However, investigation on the therapeutic perspectives of NDV, especially human immunological effects, is still ongoing.
This paper provides an overview of the current studies on the cytotoxic and anticancer effect of NDV via direct oncolysis effects or immune stimulation.
Safety of NDV strains applied for cancer immunotherapy is also discussed in this paper.
American Psychological Association (APA)
Lam, Han Yuen& Yeap, Swee Keong& Rasoli, Mehdi& Omar, Abdul Rahman& Yusoff, Khatijah& Abdul Aziz, Suraini…[et al.]. 2011. Safety and Clinical Usage of Newcastle Disease Virus in Cancer Therapy. BioMed Research International،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-990258
Modern Language Association (MLA)
Lam, Han Yuen…[et al.]. Safety and Clinical Usage of Newcastle Disease Virus in Cancer Therapy. BioMed Research International No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-990258
American Medical Association (AMA)
Lam, Han Yuen& Yeap, Swee Keong& Rasoli, Mehdi& Omar, Abdul Rahman& Yusoff, Khatijah& Abdul Aziz, Suraini…[et al.]. Safety and Clinical Usage of Newcastle Disease Virus in Cancer Therapy. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-990258
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990258