Psychological Stress Induces Temporary Masticatory Muscle Mechanical Sensitivity in Rats
Joint Authors
Wu, An-Zhen
Chen, Yong-Jin
Huang, Fei
Li, Qiang
Zhang, Min
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-01-05
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
To explore the relationship between psychological stress and masticatory muscle pain, we created a communication stress animal model to determine whether psychological stress could induce increased mechanical sensitivity in masticatory muscles and to study the changes of mechanical nociceptive thresholds after stress removal.
Forty-eight male Sprague-Dawley rats were divided into a control group (CON), a foot-shocked group (FS, including 3 subgroups recorded as FS-1, FS-2, and FS-3), a psychological stress group (PS), and a drug treatment group (DT).
PS and DT rats were confined in a communication box for one hour a day to observe the psychological responses of neighboring FS rats.Measurements of the mechanical nociceptive thresholds of the bilateral temporal and masseter muscles showed a stimulus-response relationship between psychological stress and muscle mechanical sensitivity.
The DT rats, who received a diazepam injection, showed almost the same mechanical sensitivity of the masticatory muscles to that of the control in response to psychological stress.
Fourteen days after the psychological stressor was removed, the mechanical nociceptive thresholds returned to normal.
These findings suggest that psychological stress is directly related to masticatory muscle pain.
Removal of the stressor could be a useful method for relieving mechanical sensitivity increase induced by psychological stress.
American Psychological Association (APA)
Huang, Fei& Zhang, Min& Chen, Yong-Jin& Li, Qiang& Wu, An-Zhen. 2011. Psychological Stress Induces Temporary Masticatory Muscle Mechanical Sensitivity in Rats. BioMed Research International،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-990259
Modern Language Association (MLA)
Huang, Fei…[et al.]. Psychological Stress Induces Temporary Masticatory Muscle Mechanical Sensitivity in Rats. BioMed Research International No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-990259
American Medical Association (AMA)
Huang, Fei& Zhang, Min& Chen, Yong-Jin& Li, Qiang& Wu, An-Zhen. Psychological Stress Induces Temporary Masticatory Muscle Mechanical Sensitivity in Rats. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-990259
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990259