Histone Deacetylases in Neural Stem Cells and Induced Pluripotent Stem Cells
Joint Authors
Sun, Guoqiang
Fu, Chelsea
Shi, Yanhong
Shen, Caroline
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Stem cells have provided great hope for the treatment of a variety of human diseases.
However, the molecular mechanisms underlying stem cell pluripotency, self-renewal, and differentiation remain to be unveiled.
Epigenetic regulators, including histone deacetylases (HDACs), have been shown to coordinate with cell-intrinsic transcription factors and various signaling pathways to regulate stem cell pluripotency, self-renewal, and fate determination.
This paper focuses on the role of HDACs in the proliferation and neuronal differentiation of neural stem cells and the application of HDAC inhibitors in reprogramming somatic cells to induced pluripotent stem cells (iPSCs).
It promises to be an active area of future research.
American Psychological Association (APA)
Sun, Guoqiang& Fu, Chelsea& Shen, Caroline& Shi, Yanhong. 2011. Histone Deacetylases in Neural Stem Cells and Induced Pluripotent Stem Cells. BioMed Research International،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-990331
Modern Language Association (MLA)
Sun, Guoqiang…[et al.]. Histone Deacetylases in Neural Stem Cells and Induced Pluripotent Stem Cells. BioMed Research International No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-990331
American Medical Association (AMA)
Sun, Guoqiang& Fu, Chelsea& Shen, Caroline& Shi, Yanhong. Histone Deacetylases in Neural Stem Cells and Induced Pluripotent Stem Cells. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-990331
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990331