Efficient Protein Transduction Method Using Cationic Peptides and Lipids
Joint Authors
Yamaguchi, Kei
Goshima, Naoki
Inoue, Mari
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Cationic peptides termed protein transduction domains (PTDs) have been shown to cross biological membranes efficiently.
However, proteins transduced by PTDs become entrapped within the endosomal vesicles and are not delivered into organelles.
We have developed a novel protein delivery system to enhance the proton sponge effect, which results in rupture of the endosomes, by using a mixture of Wr-T transporter peptide and a commercially available cationic lipid reagent.
This peptide and cationic lipid reagent mixture efficiently delivers a variety of cargo proteins into living cells by releasing them from the endosomes.
American Psychological Association (APA)
Yamaguchi, Kei& Inoue, Mari& Goshima, Naoki. 2011. Efficient Protein Transduction Method Using Cationic Peptides and Lipids. BioMed Research International،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-990361
Modern Language Association (MLA)
Yamaguchi, Kei…[et al.]. Efficient Protein Transduction Method Using Cationic Peptides and Lipids. BioMed Research International No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-990361
American Medical Association (AMA)
Yamaguchi, Kei& Inoue, Mari& Goshima, Naoki. Efficient Protein Transduction Method Using Cationic Peptides and Lipids. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-990361
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990361