Cytotoxic CD4 T Cells in Antiviral Immunity
Joint Authors
Marshall, Nikki B.
Swain, Susan L.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-22
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
CD4 T cells that acquire cytotoxic phenotype and function have been repeatedly identified in humans, mice, and other species in response to many diverse pathogens.
Since CD4 cytotoxic T cells are able to recognize antigenic determinants unique from those recognized by the parallel CD8 cytotoxic T cells, they can potentially contribute additional immune surveillance and direct effector function by lysing infected or malignant cells.
Here, we briefly review much of what is known about the generation of cytotoxic CD4 T cells and describe our current understanding of their role in antiviral immunity.
Furthering our understanding of the many roles of CD4 T cells during an anti-viral response is important for developing effective vaccine strategies that promote long-lasting protective immunity.
American Psychological Association (APA)
Marshall, Nikki B.& Swain, Susan L.. 2011. Cytotoxic CD4 T Cells in Antiviral Immunity. BioMed Research International،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-990416
Modern Language Association (MLA)
Marshall, Nikki B.& Swain, Susan L.. Cytotoxic CD4 T Cells in Antiviral Immunity. BioMed Research International No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-990416
American Medical Association (AMA)
Marshall, Nikki B.& Swain, Susan L.. Cytotoxic CD4 T Cells in Antiviral Immunity. BioMed Research International. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-990416
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990416