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Cross-Genome Comparisons of Newly Identified Domains in Mycoplasma gallisepticum and Domain Architectures with Other Mycoplasma species
Joint Authors
Joshi, Adwait
Sowdhamini, R.
Chilamakuri, Chandra Sekhar Reddy
Offmann, Bernard
Rani, Sane Sudha
Source
International Journal of Genomics
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-08
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Accurate functional annotation of protein sequences is hampered by important factors such as the failure of sequence search methods to identify relationships and the inherent diversity in function of proteins related at low sequence similarities.
Earlier, we had employed intermediate sequence search approach to establish new domain relationships in the unassigned regions of gene products at the whole genome level by taking Mycoplasma gallisepticum as a specific example and established new domain relationships.
In this paper, we report a detailed comparison of the conservation status of the domain and domain architectures of the gene products that bear our newly predicted domains amongst 14 other Mycoplasma genomes and reported the probable implications for the organisms.
Some of the domain associations, observed in Mycoplasma that afflict humans and other non-human primates, are involved in regulation of solute transport and DNA binding suggesting specific modes of host-pathogen interactions.
American Psychological Association (APA)
Chilamakuri, Chandra Sekhar Reddy& Joshi, Adwait& Rani, Sane Sudha& Offmann, Bernard& Sowdhamini, R.. 2011. Cross-Genome Comparisons of Newly Identified Domains in Mycoplasma gallisepticum and Domain Architectures with Other Mycoplasma species. International Journal of Genomics،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-990492
Modern Language Association (MLA)
Chilamakuri, Chandra Sekhar Reddy…[et al.]. Cross-Genome Comparisons of Newly Identified Domains in Mycoplasma gallisepticum and Domain Architectures with Other Mycoplasma species. International Journal of Genomics No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-990492
American Medical Association (AMA)
Chilamakuri, Chandra Sekhar Reddy& Joshi, Adwait& Rani, Sane Sudha& Offmann, Bernard& Sowdhamini, R.. Cross-Genome Comparisons of Newly Identified Domains in Mycoplasma gallisepticum and Domain Architectures with Other Mycoplasma species. International Journal of Genomics. 2011. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-990492
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990492