Role of Mindin in Diabetic Nephropathy

Joint Authors

Murakoshi, Maki
Funabiki, Kazuhiko
Tanimoto, Mitsuo
Tomino, Yasuhiko
Gohda, Tomohito
Horikoshi, Satoshi

Source

Journal of Diabetes Research

Issue

Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-12-26

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Diseases
Medicine

Abstract EN

A number of studies have shown that proinflammatory cytokines have important roles in determining the development of microvascular diabetic complications, including nephropathy.

Inflammatory biomarkers should be useful for diagnosis or monitoring of diabetic nephropathy.

Mindin (spondin 2) is a member of the mindin-/F-spondin family of secreted extracellular matrix (ECM) proteins.

Recent studies showed that mindin is essential for initiation of innate immune response and represents a unique pattern-recognition molecule in the ECM.

Previously, we demonstrated that the levels of urinary mindin in patients with type 2 diabetes were higher than those in healthy individuals.

We propose that urinary mindin is a potent biomarker for the development of diabetic nephropathy.

American Psychological Association (APA)

Murakoshi, Maki& Gohda, Tomohito& Tanimoto, Mitsuo& Funabiki, Kazuhiko& Horikoshi, Satoshi& Tomino, Yasuhiko. 2011. Role of Mindin in Diabetic Nephropathy. Journal of Diabetes Research،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-990638

Modern Language Association (MLA)

Murakoshi, Maki…[et al.]. Role of Mindin in Diabetic Nephropathy. Journal of Diabetes Research No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-990638

American Medical Association (AMA)

Murakoshi, Maki& Gohda, Tomohito& Tanimoto, Mitsuo& Funabiki, Kazuhiko& Horikoshi, Satoshi& Tomino, Yasuhiko. Role of Mindin in Diabetic Nephropathy. Journal of Diabetes Research. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-990638

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-990638