Obesity and Blood Pressure in 17-Year-Old Offspring of Mothers with Gestational Diabetes: Insights from the Jerusalem Perinatal Study
Joint Authors
Sagy, Yael
Sharon, Nir
Manor, Orly
Yazdgerdi, Shoshanah
Siscovick, David S.
Avgil Tsadok, Meytal
Meiner, Vardiella
Friedlander, Yechiel
Paltiel, Ora
Hochner, Hagit
Elchalal, Uriel
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-24
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Gestational diabetes mellitus (GDM) influences fetal development and offspring's metabolic risk.
We evaluated this association in 17-year-old offspring adjusting for birth weight (BW) and prepregnancy maternal BMI (mBMI).
Study Design.
The JPS birth cohort contains extensive data on 92,408 births from 1964 to 1976.
Offspring's BMI and blood pressure (BP) were obtained from military records.
For a subcohort born between 1974 and 1976, prepregnancy mBMI was available.
Offspring were classified as born to mothers with GDM (n=293) or born to mothers without recorded GDM (n=59,499).
Results.
GDM offspring had higher mean BMI and systolic and diastolic BP compared to no-recorded-GDM offspring.
After adjusting for BW, GDM remained significantly associated with offspring BMI and diastolic BP (β = 1.169 and 1.520, resp.).
In the subcohort, when prepregnancy mBMI was entered to the models, it markedly attenuated the associations with GDM.
Conclusions.
Maternal characteristics have long-term effects on cardiometabolic outcomes of their offspring aged 17 years.
American Psychological Association (APA)
Avgil Tsadok, Meytal& Friedlander, Yechiel& Paltiel, Ora& Manor, Orly& Meiner, Vardiella& Hochner, Hagit…[et al.]. 2011. Obesity and Blood Pressure in 17-Year-Old Offspring of Mothers with Gestational Diabetes: Insights from the Jerusalem Perinatal Study. Journal of Diabetes Research،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-990691
Modern Language Association (MLA)
Avgil Tsadok, Meytal…[et al.]. Obesity and Blood Pressure in 17-Year-Old Offspring of Mothers with Gestational Diabetes: Insights from the Jerusalem Perinatal Study. Journal of Diabetes Research No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-990691
American Medical Association (AMA)
Avgil Tsadok, Meytal& Friedlander, Yechiel& Paltiel, Ora& Manor, Orly& Meiner, Vardiella& Hochner, Hagit…[et al.]. Obesity and Blood Pressure in 17-Year-Old Offspring of Mothers with Gestational Diabetes: Insights from the Jerusalem Perinatal Study. Journal of Diabetes Research. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-990691
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990691