More Than Just Tumor Destruction: Immunomodulation by Thermal Ablation of Cancer
Joint Authors
Rammensee, Hans-Georg
Haen, Sebastian P.
Salih, Helmut Rainer
Pereira, Philippe L.
Gouttefangeas, Cécile
Source
Journal of Immunology Research
Issue
Vol. 2011, Issue 2011 (31 Dec. 2010), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-29
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Abstract EN
Over the past decades, thermoablative techniques for the therapy of localized tumors have gained importance in the treatment of patients not eligible for surgical resection.
Anecdotal reports have described spontaneous distant tumor regression after thermal ablation, indicating a possible involvement of the immune system, hence an induction of antitumor immunity after thermoinduced therapy.
In recent years, a growing body of evidence for modulation of both adaptive and innate immunity, as well as for the induction of danger signals through thermoablation, has emerged.
Induced immune responses, however, are mostly weak and not sufficient for the complete eradication of established tumors or durable prevention of disease progression, and combination therapies with immunomodulating drugs are being evaluated with promising results.
This article aims to summarize published findings on immune modulation through radiofrequency ablation, cryoablation, microwave ablation therapy, high-intensity focused ultrasound, and laser-induced thermotherapy.
American Psychological Association (APA)
Haen, Sebastian P.& Pereira, Philippe L.& Salih, Helmut Rainer& Rammensee, Hans-Georg& Gouttefangeas, Cécile. 2011. More Than Just Tumor Destruction: Immunomodulation by Thermal Ablation of Cancer. Journal of Immunology Research،Vol. 2011, no. 2011, pp.1-19.
https://search.emarefa.net/detail/BIM-990728
Modern Language Association (MLA)
Haen, Sebastian P.…[et al.]. More Than Just Tumor Destruction: Immunomodulation by Thermal Ablation of Cancer. Journal of Immunology Research Vol. 2011, no. 2011 (2010), pp.1-19.
https://search.emarefa.net/detail/BIM-990728
American Medical Association (AMA)
Haen, Sebastian P.& Pereira, Philippe L.& Salih, Helmut Rainer& Rammensee, Hans-Georg& Gouttefangeas, Cécile. More Than Just Tumor Destruction: Immunomodulation by Thermal Ablation of Cancer. Journal of Immunology Research. 2011. Vol. 2011, no. 2011, pp.1-19.
https://search.emarefa.net/detail/BIM-990728
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990728