Adaptive Immune Responses in Primary Cutaneous Sarcoidosis
Joint Authors
Bordignon, Matteo
Rottoli, Paola
Agostini, Carlo
Alaibac, Mauro
Source
Journal of Immunology Research
Issue
Vol. 2011, Issue 2011 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-02-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Sarcoidosis is a multisystemic inflammatory disorder with cutaneous lesions present in about one-quarter of the patients.
Cutaneous lesions have been classified as specific and nonspecific, depending on the presence of nonnecrotizing epithelial cell granulomas on histologic studies.
The development and progression of specific cutaneous sarcoidosis involves a complex interaction between cells of the adaptive immune systems, notably T-lymphocytes and dendritic cells.
In this paper, we will discuss the role of T-cells and skin dendritic cells in the development of primary cutaneous sarcoidosis and comment on the potential antigenic stimuli that may account for the development of the immunological response.
We will further explore the contributions of selected cytokines to the immunopathological process.
The knowledge of the adaptive immunological mechanisms operative in cutaneous sarcoidosis may subsequently be useful for identifying prevention and treatment strategies of systemic sarcoidosis.
American Psychological Association (APA)
Bordignon, Matteo& Rottoli, Paola& Agostini, Carlo& Alaibac, Mauro. 2011. Adaptive Immune Responses in Primary Cutaneous Sarcoidosis. Journal of Immunology Research،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-990734
Modern Language Association (MLA)
Bordignon, Matteo…[et al.]. Adaptive Immune Responses in Primary Cutaneous Sarcoidosis. Journal of Immunology Research Vol. 2011, no. 2011 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-990734
American Medical Association (AMA)
Bordignon, Matteo& Rottoli, Paola& Agostini, Carlo& Alaibac, Mauro. Adaptive Immune Responses in Primary Cutaneous Sarcoidosis. Journal of Immunology Research. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-990734
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990734