The Confluence of Stereotactic Ablative Radiotherapy and Tumor Immunology
Joint Authors
Mantz, Constantine A.
Finkelstein, Steven Eric
Hoffe, Sarah E.
Wilson, George D.
Schaue, Dörthe
McBride, William H.
Timmerman, Robert
Source
Journal of Immunology Research
Issue
Vol. 2011, Issue 2011 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-15
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Stereotactic radiation approaches are gaining more popularity for the treatment of intracranial as well as extracranial tumors in organs such as the liver and lung.
Technology, rather than biology, is driving the rapid adoption of stereotactic body radiation therapy (SBRT), also known as stereotactic ablative radiotherapy (SABR), in the clinic due to advances in precise positioning and targeting.
Dramatic improvements in tumor control have been demonstrated; however, our knowledge of normal tissue biology response mechanisms to large fraction sizes is lacking.
Herein, we will discuss how SABR can induce cellular expression of MHC I, adhesion molecules, costimulatory molecules, heat shock proteins, inflammatory mediators, immunomodulatory cytokines, and death receptors to enhance antitumor immune responses.
American Psychological Association (APA)
Finkelstein, Steven Eric& Timmerman, Robert& McBride, William H.& Schaue, Dörthe& Hoffe, Sarah E.& Mantz, Constantine A.…[et al.]. 2011. The Confluence of Stereotactic Ablative Radiotherapy and Tumor Immunology. Journal of Immunology Research،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-990796
Modern Language Association (MLA)
Finkelstein, Steven Eric…[et al.]. The Confluence of Stereotactic Ablative Radiotherapy and Tumor Immunology. Journal of Immunology Research Vol. 2011, no. 2011 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-990796
American Medical Association (AMA)
Finkelstein, Steven Eric& Timmerman, Robert& McBride, William H.& Schaue, Dörthe& Hoffe, Sarah E.& Mantz, Constantine A.…[et al.]. The Confluence of Stereotactic Ablative Radiotherapy and Tumor Immunology. Journal of Immunology Research. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-990796
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990796