Asbestos Induces Reduction of Tumor Immunity
Joint Authors
Chen, Ying
Lee, Suni
Hiratsuka, Junichi
Maeda, Megumi
Otsuki, Takemi
Nishimura, Yasumitsu
Matsuzaki, Hidenori
Kumagai-Takei, Naoko
Source
Journal of Immunology Research
Issue
Vol. 2011, Issue 2011 (31 Dec. 2010), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-04
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Asbestos-related cancers such as malignant mesothelioma and lung cancer are an important issue in the world.
There are many conflicts concerning economical considerations and medical evidence for these cancers and much confusion regarding details of the pathological mechanisms of asbestos-induced cancers.
For example, there is uncertainty concerning the degree of danger of the iron-absent chrysotile compared with iron-containing crocidolite and amosite.
However, regarding bad prognosis of mesothelioma, medical approaches to ensure the recognition of the biological effects of asbestos and the pathological mechanisms of asbestos-induced carcinogenesis, as well as clinical trials to detect the early stage of mesothelioma, should result in better preventions and the cure of these malignancies.
We have been investigating the immunological effects of asbestos in relation to the reduction of tumor immunity.
In this paper, cellular and molecular approaches to clarify the immunological effects of asbestos are described, and all the findings indicate that the reduction of tumor immunity is caused by asbestos exposure and involvement in asbestos-induced cancers.
These investigations may not only allow the clear recognition of the biological effects of asbestos, but also present a novel procedure for early detection of previous asbestos exposure and the presence of mesothelioma as well as the chemoprevention of asbestos-related cancers.
American Psychological Association (APA)
Kumagai-Takei, Naoko& Maeda, Megumi& Chen, Ying& Matsuzaki, Hidenori& Lee, Suni& Nishimura, Yasumitsu…[et al.]. 2011. Asbestos Induces Reduction of Tumor Immunity. Journal of Immunology Research،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-990801
Modern Language Association (MLA)
Kumagai-Takei, Naoko…[et al.]. Asbestos Induces Reduction of Tumor Immunity. Journal of Immunology Research Vol. 2011, no. 2011 (2010), pp.1-9.
https://search.emarefa.net/detail/BIM-990801
American Medical Association (AMA)
Kumagai-Takei, Naoko& Maeda, Megumi& Chen, Ying& Matsuzaki, Hidenori& Lee, Suni& Nishimura, Yasumitsu…[et al.]. Asbestos Induces Reduction of Tumor Immunity. Journal of Immunology Research. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-990801
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990801