Molecular and Immunological Characterization of Staphylococcus aureus in Pediatric Atopic Dermatitis: Implications for Prophylaxis and Clinical Management
Joint Authors
Stefani, Stefania
Bordignon, Valentina
De Santis, Alessandra
Pecetta, Simone
Prignano, Grazia
Capitanio, Bruno
Cordiali-Fei, Paola
Ensoli, Fabrizio
Pascolini, Chiara
Cilli, Laura
Cafiso, Viviana
Passariello, Claudio
Sinagra, JoLinda
Source
Journal of Immunology Research
Issue
Vol. 2011, Issue 2011 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
S.
aureus represents a critical cofactor in atopic dermatitis (AD).
In this paper, the prevalence of S.
aureus infection/colonization was evaluated in 117 children as well as in their cohabitants, in order to assess the value of S.
aureus characterization in predicting disease onset and severity and in providing indications for prophylaxis.
Results showed that children with AD as well as their cohabitants had a significantly greater incidence of S.
aureus infection/colonization as compared to controls.
The genetic characterization showed a virtual identity of the bacteria strains collected at different sites of the patients with those found in the cohabitants, suggesting both a direct transmission between the nasal reservoir and the lesions in the same atopic subject and a risk for reinfection within family cohabitants.
These data stress the need of preliminary laboratory assessment and posttherapy control in both AD patients and their close contacts for effective S.
aureus eradication.
American Psychological Association (APA)
Pascolini, Chiara& Sinagra, JoLinda& Pecetta, Simone& Bordignon, Valentina& De Santis, Alessandra& Cilli, Laura…[et al.]. 2011. Molecular and Immunological Characterization of Staphylococcus aureus in Pediatric Atopic Dermatitis: Implications for Prophylaxis and Clinical Management. Journal of Immunology Research،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-990851
Modern Language Association (MLA)
Pascolini, Chiara…[et al.]. Molecular and Immunological Characterization of Staphylococcus aureus in Pediatric Atopic Dermatitis: Implications for Prophylaxis and Clinical Management. Journal of Immunology Research Vol. 2011, no. 2011 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-990851
American Medical Association (AMA)
Pascolini, Chiara& Sinagra, JoLinda& Pecetta, Simone& Bordignon, Valentina& De Santis, Alessandra& Cilli, Laura…[et al.]. Molecular and Immunological Characterization of Staphylococcus aureus in Pediatric Atopic Dermatitis: Implications for Prophylaxis and Clinical Management. Journal of Immunology Research. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-990851
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-990851