Dopamine-Induced Nonmotor Symptoms of Parkinson's Disease
Joint Authors
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-20
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Nonmotor symptoms of Parkinson's disease (PD) may emerge secondary to the underlying pathogenesis of the disease, while others are recognized side effects of treatment.
Inevitably, there is an overlap as the disease advances and patients require higher dosages and more complex medical regimens.
The non-motor symptoms that emerge secondary to dopaminergic therapy encompass several domains, including neuropsychiatric, autonomic, and sleep.
These are detailed in the paper.
Neuropsychiatric complications include hallucinations and psychosis.
In addition, compulsive behaviors, such as pathological gambling, hypersexuality, shopping, binge eating, and punding, have been shown to have a clear association with dopaminergic medications.
Dopamine dysregulation syndrome (DDS) is a compulsive behavior that is typically viewed through the lens of addiction, with patients needing escalating dosages of dopamine replacement therapy.
Treatment side effects on the autonomic system include nausea, orthostatic hypotension, and constipation.
Sleep disturbances include fragmented sleep, nighttime sleep problems, daytime sleepiness, and sleep attacks.
Recognizing the non-motor symptoms that can arise specifically from dopamine therapy is useful to help optimize treatment regimens for this complex disease.
American Psychological Association (APA)
Park, Ariane& Stacy, Mark. 2011. Dopamine-Induced Nonmotor Symptoms of Parkinson's Disease. Parkinson’s Disease،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-991064
Modern Language Association (MLA)
Park, Ariane& Stacy, Mark. Dopamine-Induced Nonmotor Symptoms of Parkinson's Disease. Parkinson’s Disease No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-991064
American Medical Association (AMA)
Park, Ariane& Stacy, Mark. Dopamine-Induced Nonmotor Symptoms of Parkinson's Disease. Parkinson’s Disease. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-991064
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991064