Influence of Different Cut-Off Values on the Diagnosis of Mild Cognitive Impairment in Parkinson's Disease
Joint Authors
Maetzler, Walter
Gaenslen, Alexandra
Berg, Daniela
Feseker, Anne
Liepelt-Scarfone, Inga
Godau, Jana
Graeber, Susanne
Baysal, Gülsüm
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Comparable to Alzheimer's disease, mild cognitive impairment in Parkinson's disease (PD-MCI) is associated with an increased risk for dementia.
However different definitions of PD-MCI may have varying predictive accuracy for dementia.
In a cohort of 101 nondemented Parkinson patients who underwent neuropsychological testing, the frequency of PD-MCI subjects and PD-MCI subtypes (i.e., amnestic/nonamnestic) was determined by use of varying healthy population-based cut-off values.
We also investigated the association between defined PD-MCI groups and ADL scales.
Varying cut-off values for the definition of PD-MCI were found to affect frequency of PD-MCI subjects (9.9%–92.1%) and, maybe more important, lead to a “shift” of proportion of detected PD-MCI subtypes especially within the amnestic single-domain subtype.
Models using a strict cut-off value were significantly associated with lower ADL scores.
Thus, the use of defined cut-off values for the definition of PD-MCI is highly relevant for comparison purposes.
Strict cut-off values may have a higher predictive value for dementia.
American Psychological Association (APA)
Liepelt-Scarfone, Inga& Graeber, Susanne& Feseker, Anne& Baysal, Gülsüm& Godau, Jana& Gaenslen, Alexandra…[et al.]. 2011. Influence of Different Cut-Off Values on the Diagnosis of Mild Cognitive Impairment in Parkinson's Disease. Parkinson’s Disease،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-991069
Modern Language Association (MLA)
Liepelt-Scarfone, Inga…[et al.]. Influence of Different Cut-Off Values on the Diagnosis of Mild Cognitive Impairment in Parkinson's Disease. Parkinson’s Disease No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-991069
American Medical Association (AMA)
Liepelt-Scarfone, Inga& Graeber, Susanne& Feseker, Anne& Baysal, Gülsüm& Godau, Jana& Gaenslen, Alexandra…[et al.]. Influence of Different Cut-Off Values on the Diagnosis of Mild Cognitive Impairment in Parkinson's Disease. Parkinson’s Disease. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-991069
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991069