Deep Brain Stimulation of Caudal Zona Incerta and Subthalamic Nucleus in Patients with Parkinson's Disease: Effects on Diadochokinetic Rate
Joint Authors
Unger, Elin
Zafar, Hamayun
Nordh, Erik
Wahlgren, Sofia
van Doorn, Jan
Karlsson, Fredrik
Linder, Jan
Blomstedt, Patric
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-28
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The hypokinetic dysarthria observed in Parkinson's disease (PD) affects the range, speed, and accuracy of articulatory gestures in patients, reducing the perceived quality of speech acoustic output in continuous speech.
Deep brain stimulation (DBS) of the subthalamic nucleus (STN-DBS) and of the caudal zona incerta (cZi-DBS) are current surgical treatment options for PD.
This study aimed at investigating the outcome of STN-DBS (7 patients) and cZi-DBS (7 patients) in two articulatory diadochokinesis tasks (AMR and SMR) using measurements of articulation rate and quality of the plosive consonants (using the percent measurable VOT metric).
The results indicate that patients receiving STN-DBS increased in articulation rate in the Stim-ON condition in the AMR task only, with no effect on production quality.
Patients receiving cZi-DBS decreased in articulation rate in the Stim-ON condition and further showed a reduction in production quality.
The data therefore suggest that cZi-DBS is more detrimental for extended articulatory movements than STN-DBS.
American Psychological Association (APA)
Karlsson, Fredrik& Unger, Elin& Wahlgren, Sofia& Blomstedt, Patric& Linder, Jan& Nordh, Erik…[et al.]. 2011. Deep Brain Stimulation of Caudal Zona Incerta and Subthalamic Nucleus in Patients with Parkinson's Disease: Effects on Diadochokinetic Rate. Parkinson’s Disease،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-991072
Modern Language Association (MLA)
Karlsson, Fredrik…[et al.]. Deep Brain Stimulation of Caudal Zona Incerta and Subthalamic Nucleus in Patients with Parkinson's Disease: Effects on Diadochokinetic Rate. Parkinson’s Disease No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-991072
American Medical Association (AMA)
Karlsson, Fredrik& Unger, Elin& Wahlgren, Sofia& Blomstedt, Patric& Linder, Jan& Nordh, Erik…[et al.]. Deep Brain Stimulation of Caudal Zona Incerta and Subthalamic Nucleus in Patients with Parkinson's Disease: Effects on Diadochokinetic Rate. Parkinson’s Disease. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-991072
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991072