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Traditional Chinese Medicine Improves Activities of Daily Living in Parkinson's Disease
Joint Authors
Fang, Zhenglong
Qin, Baofeng
Yamamoto, Yoshiharu
Sun, Yan
Kwak, Shin
Liu, Yun
Pan, Weidong
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We evaluated the effects of a traditional Chinese medicine (TCM), named Zeng-xiao An-shen Zhi-chan 2 (ZAZ2), on patients with Parkinson's disease (PD).
Among 115 patients with idiopathic PD enrolled (mean age, 64.7 ± 10.2 years old), 110 patients (M = 65, F = 45; mean age, 64.9 ± 10.7 years old) completed the study.
Patients took either ZAZ2 (n=59) or placebo granule (n=56) in a blind manner for 13 weeks while maintaining other anti-Parkinson medications unchanged.
All participants wore a motion logger, and we analyzed the power-law temporal autocorrelation of the motion logger records taken on 3 occasions (before, one week, and 13 weeks after the drug administration).
Drug efficacy was evaluated with the conventional Unified Parkinson Disease Rating Scale (UPDRS), as well as the power-law exponent α, which corresponds to the level of physical activity of the patients.
ZAZ2 but not placebo granule improved the awake-sleep rhythm, the UPDRS Part II, Part II + III, and Part IV scores, and the α values.
The results indicate that ZAZ2 improved activities of daily living (ADL) of parkinsonism and, thus, is a potentially suitable drug for long-term use.
American Psychological Association (APA)
Pan, Weidong& Kwak, Shin& Liu, Yun& Sun, Yan& Fang, Zhenglong& Qin, Baofeng…[et al.]. 2011. Traditional Chinese Medicine Improves Activities of Daily Living in Parkinson's Disease. Parkinson’s Disease،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-991113
Modern Language Association (MLA)
Pan, Weidong…[et al.]. Traditional Chinese Medicine Improves Activities of Daily Living in Parkinson's Disease. Parkinson’s Disease No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-991113
American Medical Association (AMA)
Pan, Weidong& Kwak, Shin& Liu, Yun& Sun, Yan& Fang, Zhenglong& Qin, Baofeng…[et al.]. Traditional Chinese Medicine Improves Activities of Daily Living in Parkinson's Disease. Parkinson’s Disease. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-991113
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991113