Idiopathic REM Sleep Behavior Disorder: Implications for the Pathogenesis of Lewy Body Diseases
Joint Authors
Miyamoto, Tomoyuki
Iwanami, Masaoki
Miyamoto, Masayuki
Hirata, Koichi
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-21
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
|Objectives.
Both results of the odor identification and cardiac 123I-metaiodobenzylguanidine accumulation have been investigated for their potential to enhance the detection of pathogenesis resembling that of Lewy body-related α-synucleinopathies in patients clinically diagnosed as having idiopathic REM sleep behavior disorder.
Methods.
We performed both the Odor Stick Identification Test for Japanese and 123I-metaiodobenzylguanidine scintigraphy in 30 patients with idiopathic REM sleep behavior disorder, 38 patients with Parkinson's disease, and 20 control subjects.
Results.
In idiopathic REM sleep behavior disorder, reduced odor identification score and an early or delayed heart to mediastinum ratio on 123I-metaiodobenzylguanidine were almost as severe as in Parkinson's disease patients.
Delayed cardiac 123I-metaiodobenzylguanidine uptake was even more severe in the idiopathic REM sleep behavior disorder group than in the Parkinson's disease group.
Conclusions.
Reduced cardiac 123I-metaiodobenzylguanidine uptake, which is independent of parkinsonism, may be more closely associated with idiopathic REM sleep behavior disorder than olfactory impairment.
American Psychological Association (APA)
Miyamoto, Tomoyuki& Miyamoto, Masayuki& Iwanami, Masaoki& Hirata, Koichi. 2011. Idiopathic REM Sleep Behavior Disorder: Implications for the Pathogenesis of Lewy Body Diseases. Parkinson’s Disease،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-991125
Modern Language Association (MLA)
Miyamoto, Tomoyuki…[et al.]. Idiopathic REM Sleep Behavior Disorder: Implications for the Pathogenesis of Lewy Body Diseases. Parkinson’s Disease No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-991125
American Medical Association (AMA)
Miyamoto, Tomoyuki& Miyamoto, Masayuki& Iwanami, Masaoki& Hirata, Koichi. Idiopathic REM Sleep Behavior Disorder: Implications for the Pathogenesis of Lewy Body Diseases. Parkinson’s Disease. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-991125
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991125