Symptom Burden, Survival and Palliative Care in Advanced Soft Tissue Sarcoma
Joint Authors
Judson, Ian R.
Ross, Joy R.
Smith, Clare
Gough, Nicholas J.
Riley, Julia
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The symptom burden and role of palliative care (PC) in patients with advanced soft tissue sarcoma (STS) are not well defined.
Methods.
This study retrospectively reviewed both symptoms and PC involvement in patients known to an STS referral centre who died in one calendar year.
Results.
81 patients met inclusion criteria of which 27% had locally advanced disease and 73% metastases at initial referral.
The median number of symptoms was slowly progressive ranging from 2 (range 0–5) before first-line chemotherapy (n=50) to 3 (range 1–6) at the time of best supportive care (BSC) decision (n=48).
Pain and dyspnoea were the commonest symptoms.
Median overall survival from BSC decision was 3.4 weeks.
88% had PC involvement (either hospital, community, or both) with median time from first PC referral to death of 16 (range 0–110) weeks.
Conclusions.
Patients with metastatic STS have a significant symptom burden which justifies early PC referral.
Pain, including neuropathic pain, is a significant problem.
Dyspnoea is common, progressive and appears to be undertreated.
Time from BSC decision to death is short, and prospective studies are required to determine whether this is due to overtreatment or very rapid terminal disease progression.
American Psychological Association (APA)
Gough, Nicholas J.& Smith, Clare& Ross, Joy R.& Riley, Julia& Judson, Ian R.. 2011. Symptom Burden, Survival and Palliative Care in Advanced Soft Tissue Sarcoma. Complexity،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-991163
Modern Language Association (MLA)
Gough, Nicholas J.…[et al.]. Symptom Burden, Survival and Palliative Care in Advanced Soft Tissue Sarcoma. Complexity No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-991163
American Medical Association (AMA)
Gough, Nicholas J.& Smith, Clare& Ross, Joy R.& Riley, Julia& Judson, Ian R.. Symptom Burden, Survival and Palliative Care in Advanced Soft Tissue Sarcoma. Complexity. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-991163
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991163