Update on Chemotherapy in the Treatment of Urothelial Carcinoma
Joint Authors
Costantini, Carrie
Millard, Frederick
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-19
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Urothelial carcinoma is the fifth most common malignancy diagnosed each year in the United States.
Neoadjuvant and adjuvant chemotherapy are given to decrease the risk of recurrent or metastatic disease with the more robust clinical data supporting the former.
Bladder preservation utilizes a trimodality approach with maximal transurethral resection followed by concurrent chemotherapy and radiation and is appropriate for select patients.
Gemcitabine and cisplatin is the current standard of care for first-line treatment in fit patients with metastatic disease.
Optimal second-line therapy remains undefined, and targeted agents are under investigation.
Clinical trial participation should be encouraged in patients with urothelial carcinoma of the bladder to help improve treatment regimens and outcomes.
Synopsis.
Chemotherapy is commonly used in the treatment of urothelial carcinoma of the bladder.
This paper will review the role of chemotherapy in the neoadjuvant, adjuvant, bladder sparing, and metastatic settings.
American Psychological Association (APA)
Costantini, Carrie& Millard, Frederick. 2011. Update on Chemotherapy in the Treatment of Urothelial Carcinoma. The Scientific World Journal،Vol. 2011, no. 2011, pp.1-14.
https://search.emarefa.net/detail/BIM-991329
Modern Language Association (MLA)
Costantini, Carrie& Millard, Frederick. Update on Chemotherapy in the Treatment of Urothelial Carcinoma. The Scientific World Journal No. 2011 (2011), pp.1-14.
https://search.emarefa.net/detail/BIM-991329
American Medical Association (AMA)
Costantini, Carrie& Millard, Frederick. Update on Chemotherapy in the Treatment of Urothelial Carcinoma. The Scientific World Journal. 2011. Vol. 2011, no. 2011, pp.1-14.
https://search.emarefa.net/detail/BIM-991329
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991329