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Comparison of Next-Generation Sequencing Systems
Joint Authors
Li, Yinhu
He, Yimin
Law, Maggie
Lin, Danni
Lu, Lihua
Pong, Ray
Hu, Ni
Li, Siliang
Liu, Lin
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-05
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
With fast development and wide applications of next-generation sequencing (NGS) technologies, genomic sequence information is within reach to aid the achievement of goals to decode life mysteries, make better crops, detect pathogens, and improve life qualities.
NGS systems are typically represented by SOLiD/Ion Torrent PGM from Life Sciences, Genome Analyzer/HiSeq 2000/MiSeq from Illumina, and GS FLX Titanium/GS Junior from Roche.
Beijing Genomics Institute (BGI), which possesses the world’s biggest sequencing capacity, has multiple NGS systems including 137 HiSeq 2000, 27 SOLiD, one Ion Torrent PGM, one MiSeq, and one 454 sequencer.
We have accumulated extensive experience in sample handling, sequencing, and bioinformatics analysis.
In this paper, technologies of these systems are reviewed, and first-hand data from extensive experience is summarized and analyzed to discuss the advantages and specifics associated with each sequencing system.
At last, applications of NGS are summarized.
American Psychological Association (APA)
Liu, Lin& Li, Yinhu& Li, Siliang& Hu, Ni& He, Yimin& Pong, Ray…[et al.]. 2012. Comparison of Next-Generation Sequencing Systems. BioMed Research International،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-991515
Modern Language Association (MLA)
Liu, Lin…[et al.]. Comparison of Next-Generation Sequencing Systems. BioMed Research International No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-991515
American Medical Association (AMA)
Liu, Lin& Li, Yinhu& Li, Siliang& Hu, Ni& He, Yimin& Pong, Ray…[et al.]. Comparison of Next-Generation Sequencing Systems. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-991515
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991515