Are Basophils Important Mediators for Helminth-Induced Th2 Immune Responses? A Debate
Joint Authors
Flisser, Ana
Leon-Cabrera, Sonia
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Helminth parasites induce Th2 immune responses.
Immunological mechanisms leading to Th2 induction are mainly dependent on IL-4.
However, early source of IL-4 has not been precisely identified.
Noticeably, basophils seem to be important mediators for inducing and maintaining the Th2 response probably because they secrete IL-4 and exert functions similar to APCs.
Nevertheless, recent experimental evidence points that DCs could be also significant participants during this process.
The involvement of basophils during memory responses is also discussed.
American Psychological Association (APA)
Leon-Cabrera, Sonia& Flisser, Ana. 2012. Are Basophils Important Mediators for Helminth-Induced Th2 Immune Responses? A Debate. BioMed Research International،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-991614
Modern Language Association (MLA)
Leon-Cabrera, Sonia& Flisser, Ana. Are Basophils Important Mediators for Helminth-Induced Th2 Immune Responses? A Debate. BioMed Research International No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-991614
American Medical Association (AMA)
Leon-Cabrera, Sonia& Flisser, Ana. Are Basophils Important Mediators for Helminth-Induced Th2 Immune Responses? A Debate. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-991614
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991614