Antihyperglycemic Effects of Fermented and Nonfermented Mung Bean Extracts on Alloxan-Induced-Diabetic Mice
Joint Authors
Alitheen, Noorjahan Banu Mohamed
Beh, Boon Kee
Mohd Ali, Norlaily
Koh, Soo Peng
Ho, Wan Yong
Long, Kamariah
Yeap, Swee Keong
Mohd Yusof, Hamidah
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Mung bean was reported as a potential antidiabetic agent while fermented food has been proposed as one of the major contributors that can reduce the risk of diabetes in Asian populations.
In this study, we have compared the normoglycemic effect, glucose-induced hyperglycemic effect, and alloxan-induced hyperglycemic effect of fermented and nonfermented mung bean extracts.
Our results showed that fermented mung bean extracts did not induce hypoglycemic effect on normal mice but significantly reduced the blood sugar levels of glucose- and alloxan-induced hyperglycemic mice.
The serum levels of cholesterol, triglyceride (TG), and low-density lipoprotein (LDL) were also lowered while insulin secretion and antioxidant level as measured by malonaldehyde (MDA) assays were significantly improved in the plasma of the fermented mung bean-treated group in alloxan-induced hyperglycemic mouse.
These results indicated that fermentation using Mardi Rhizopus sp.
strain 5351 inoculums could enhance the antihyperglycemic and the antioxidant effects of mung bean in alloxan-treated mice.
The improvement in the antihyperglycemic effect may also be contributed by the increased content of GABA and the free amino acid that are present in the fermented mung bean extracts.
American Psychological Association (APA)
Yeap, Swee Keong& Mohd Ali, Norlaily& Mohd Yusof, Hamidah& Alitheen, Noorjahan Banu Mohamed& Beh, Boon Kee& Ho, Wan Yong…[et al.]. 2012. Antihyperglycemic Effects of Fermented and Nonfermented Mung Bean Extracts on Alloxan-Induced-Diabetic Mice. BioMed Research International،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-991620
Modern Language Association (MLA)
Yeap, Swee Keong…[et al.]. Antihyperglycemic Effects of Fermented and Nonfermented Mung Bean Extracts on Alloxan-Induced-Diabetic Mice. BioMed Research International No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-991620
American Medical Association (AMA)
Yeap, Swee Keong& Mohd Ali, Norlaily& Mohd Yusof, Hamidah& Alitheen, Noorjahan Banu Mohamed& Beh, Boon Kee& Ho, Wan Yong…[et al.]. Antihyperglycemic Effects of Fermented and Nonfermented Mung Bean Extracts on Alloxan-Induced-Diabetic Mice. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-991620
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991620