Sarcomere Imaging by Quantum Dots for the Study of Cardiac Muscle Physiology
Joint Authors
Kurihara, Satoshi
Mizuno, Akari
Oyama, Kotaro
Shimozawa, Togo
Kobirumaki-Shimozawa, Fuyu
Serizawa, Takahiro
Fukuda, Norio
Kagemoto, Tatsuya
Ishiwata, Shin'ichi
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We here review the use of quantum dots (QDs) for the imaging of sarcomeric movements in cardiac muscle.
QDs are fluorescence substances (CdSe) that absorb photons and reemit photons at a different wavelength (depending on the size of the particle); they are efficient in generating long-lasting, narrow symmetric emission profiles, and hence useful in various types of imaging studies.
Recently, we developed a novel system in which the length of a particular, single sarcomere in cardiomyocytes can be measured at ~30 nm precision.
Moreover, our system enables accurate measurement of sarcomere length in the isolated heart.
We propose that QDs are the ideal tool for the study of sarcomere dynamics during excitation-contraction coupling in healthy and diseased cardiac muscle.
American Psychological Association (APA)
Kobirumaki-Shimozawa, Fuyu& Oyama, Kotaro& Serizawa, Takahiro& Mizuno, Akari& Kagemoto, Tatsuya& Shimozawa, Togo…[et al.]. 2012. Sarcomere Imaging by Quantum Dots for the Study of Cardiac Muscle Physiology. BioMed Research International،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-991638
Modern Language Association (MLA)
Kobirumaki-Shimozawa, Fuyu…[et al.]. Sarcomere Imaging by Quantum Dots for the Study of Cardiac Muscle Physiology. BioMed Research International No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-991638
American Medical Association (AMA)
Kobirumaki-Shimozawa, Fuyu& Oyama, Kotaro& Serizawa, Takahiro& Mizuno, Akari& Kagemoto, Tatsuya& Shimozawa, Togo…[et al.]. Sarcomere Imaging by Quantum Dots for the Study of Cardiac Muscle Physiology. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-991638
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991638