Thin-Layer Hydroxyapatite Deposition on a Nanofiber Surface Stimulates Mesenchymal Stem Cell Proliferation and Their Differentiation into Osteoblasts
Joint Authors
Kocourek, Tomáš
Jelínek, Miroslav
Tvrdík, Daniel
Buzgo, Matej
Amler, Evžen
Vysloužilová, Lucie
Lukáš, David
Kochová, Petra
Rampichová, Michala
Prosecká, Eva
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-29
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Pulsed laser deposition was proved as a suitable method for hydroxyapatite (HA) coating of coaxial poly-ɛ-caprolactone/polyvinylalcohol (PCL/PVA) nanofibers.
The fibrous morphology of PCL/PVA nanofibers was preserved, if the nanofiber scaffold was coated with thin layers of HA (200 nm and 400 nm).
Increasing thickness of HA, however, resulted in a gradual loss of fibrous character.
In addition, biomechanical properties were improved after HA deposition on PCL/PVA nanofibers as the value of Young's moduli of elasticity significantly increased.
Clearly, thin-layer hydroxyapatite deposition on a nanofiber surface stimulated mesenchymal stem cell viability and their differentiation into osteoblasts.
The optimal depth of HA was 800 nm.
American Psychological Association (APA)
Prosecká, Eva& Buzgo, Matej& Rampichová, Michala& Kocourek, Tomáš& Kochová, Petra& Vysloužilová, Lucie…[et al.]. 2012. Thin-Layer Hydroxyapatite Deposition on a Nanofiber Surface Stimulates Mesenchymal Stem Cell Proliferation and Their Differentiation into Osteoblasts. BioMed Research International،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-991698
Modern Language Association (MLA)
Prosecká, Eva…[et al.]. Thin-Layer Hydroxyapatite Deposition on a Nanofiber Surface Stimulates Mesenchymal Stem Cell Proliferation and Their Differentiation into Osteoblasts. BioMed Research International No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-991698
American Medical Association (AMA)
Prosecká, Eva& Buzgo, Matej& Rampichová, Michala& Kocourek, Tomáš& Kochová, Petra& Vysloužilová, Lucie…[et al.]. Thin-Layer Hydroxyapatite Deposition on a Nanofiber Surface Stimulates Mesenchymal Stem Cell Proliferation and Their Differentiation into Osteoblasts. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-991698
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991698
