De Novo Kidney Regeneration with Stem Cells
Joint Authors
Yokote, Shinya
Yamanaka, Shuichiro
Yokoo, Takashi
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-26
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Recent studies have reported on techniques to mobilize and activate endogenous stem-cells in injured kidneys or to introduce exogenous stem cells for tissue repair.
Despite many recent advantages in renal regenerative therapy, chronic kidney disease (CKD) remains a major cause of morbidity and mortality and the number of CKD patients has been increasing.
When the sophisticated structure of the kidneys is totally disrupted by end stage renal disease (ESRD), traditional stem cell-based therapy is unable to completely regenerate the damaged tissue.
This suggests that whole organ regeneration may be a promising therapeutic approach to alleviate patients with uncured CKD.
We summarize here the potential of stem-cell-based therapy for injured tissue repair and de novo whole kidney regeneration.
In addition, we describe the hurdles that must be overcome and possible applications of this approach in kidney regeneration.
American Psychological Association (APA)
Yokote, Shinya& Yamanaka, Shuichiro& Yokoo, Takashi. 2012. De Novo Kidney Regeneration with Stem Cells. BioMed Research International،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-991707
Modern Language Association (MLA)
Yokote, Shinya…[et al.]. De Novo Kidney Regeneration with Stem Cells. BioMed Research International No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-991707
American Medical Association (AMA)
Yokote, Shinya& Yamanaka, Shuichiro& Yokoo, Takashi. De Novo Kidney Regeneration with Stem Cells. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-991707
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991707