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Development of Animal Model for Studying Deep Second-Degree Thermal Burns
Joint Authors
dos Anjos Carneiro-Leão, Ana Maria
dos Santos Correia, Maria Tereza
dos Santos Tavares Pereira, Danielle
de Pontes-Filho, Nicodemos Teles
Madruga Lima-Ribeiro, Maria Helena
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-12
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Thermal lesions were produced in 12 male Wistar rats, positioning a massive aluminum bar 10 mm in diameter (51 g), preheated to 99°C ± 2°C/10 min.
on the back of each animal for 15 sec.
After 7, 14, 21, and 28 days, animals were euthanized.
The edema intensity was mild, with no bubble and formation of a thick and dry crust from the 3rd day.
The percentage of tissue shrinkage at 28 days was 66.67 ± 1.66%.
There was no sign of infection, bleeding, or secretion.
Within 28 days reepithelialization was incomplete, with fibroblastic proliferation and moderate fibrosis and presence of modeled dense collagen fibers.
It is concluded that the model established is applicable in obtaining deep second-degree thermal burns in order to evaluate the healing action of therapeutic agents of topical use.
American Psychological Association (APA)
dos Santos Tavares Pereira, Danielle& Madruga Lima-Ribeiro, Maria Helena& de Pontes-Filho, Nicodemos Teles& dos Anjos Carneiro-Leão, Ana Maria& dos Santos Correia, Maria Tereza. 2012. Development of Animal Model for Studying Deep Second-Degree Thermal Burns. BioMed Research International،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-991711
Modern Language Association (MLA)
dos Santos Tavares Pereira, Danielle…[et al.]. Development of Animal Model for Studying Deep Second-Degree Thermal Burns. BioMed Research International No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-991711
American Medical Association (AMA)
dos Santos Tavares Pereira, Danielle& Madruga Lima-Ribeiro, Maria Helena& de Pontes-Filho, Nicodemos Teles& dos Anjos Carneiro-Leão, Ana Maria& dos Santos Correia, Maria Tereza. Development of Animal Model for Studying Deep Second-Degree Thermal Burns. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-991711
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991711