The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis

Joint Authors

Antunes, Ricardo F.
Dumitriu, Ingrid E.
Kaski, Juan Carlos

Source

BioMed Research International

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-16, 16 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-12-22

Country of Publication

Egypt

No. of Pages

16

Main Subjects

Medicine

Abstract EN

Atherosclerosis is a chronic inflammatory disease that is mediated by both the innate and adaptive immune responses.

T lymphocytes, that together with B cells are the cellular effectors of the adaptive immune system, are currently endowed with crucial roles in the development and progression of atherosclerosis.

Costimulatory receptors are a class of molecules expressed by T lymphocytes that regulate the activation of T cells and the generation of effector T-cell responses.

In this review we present the roles of costimulatory receptors of the tumour necrosis factor receptor (TNFR) superfamily in atherosclerosis and discuss the implications for future therapies that could be used to specifically modulate the immune response of pathogenic T cells in this disease.

American Psychological Association (APA)

Antunes, Ricardo F.& Kaski, Juan Carlos& Dumitriu, Ingrid E.. 2011. The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis. BioMed Research International،Vol. 2012, no. 2012, pp.1-16.
https://search.emarefa.net/detail/BIM-991714

Modern Language Association (MLA)

Antunes, Ricardo F.…[et al.]. The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis. BioMed Research International No. 2012 (2012), pp.1-16.
https://search.emarefa.net/detail/BIM-991714

American Medical Association (AMA)

Antunes, Ricardo F.& Kaski, Juan Carlos& Dumitriu, Ingrid E.. The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis. BioMed Research International. 2011. Vol. 2012, no. 2012, pp.1-16.
https://search.emarefa.net/detail/BIM-991714

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-991714