Various Jobs of Proteolytic Enzymes in Skeletal Muscle during Unloading: Facts and Speculations
Joint Authors
Kachaeva, E. V.
Shenkman, B. S.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-08
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Skeletal muscles, namely, postural muscles, as soleus, suffer from atrophy under disuse.
Muscle atrophy development caused by unloading differs from that induced by denervation or other stimuli.
Disuse atrophy is supposed to be the result of shift of protein synthesis/proteolysis balance towards protein degradation increase.
Maintaining of the balance involves many systems of synthesis and proteolysis, whose activation leads to muscle adaptation to disuse rather than muscle degeneration.
Here, we review recent data on activity of signaling systems involved in muscle atrophy development under unloading and muscle adaptation to the lack of support.
American Psychological Association (APA)
Kachaeva, E. V.& Shenkman, B. S.. 2012. Various Jobs of Proteolytic Enzymes in Skeletal Muscle during Unloading: Facts and Speculations. BioMed Research International،Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-991734
Modern Language Association (MLA)
Kachaeva, E. V.& Shenkman, B. S.. Various Jobs of Proteolytic Enzymes in Skeletal Muscle during Unloading: Facts and Speculations. BioMed Research International No. 2012 (2012), pp.1-15.
https://search.emarefa.net/detail/BIM-991734
American Medical Association (AMA)
Kachaeva, E. V.& Shenkman, B. S.. Various Jobs of Proteolytic Enzymes in Skeletal Muscle during Unloading: Facts and Speculations. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-991734
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991734