Cancer Chemoprevention by Citrus Pulp and Juices Containing High Amounts of β-Cryptoxanthin and Hesperidin
Joint Authors
Tanaka, Takuji
Tanaka, Mayu
Tanaka, Takahiro
Kuno, Toshiya
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-24
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
β-Cryptoxanthin, a carotenoid, and hesperidin, a flavonoid, possess inhibitory effects on carcinogenesis in several tissues.
We recently have prepared a pulp (CHRP) and citrus juices (MJ2 and MJ5) from a satsuma mandarin (Citrus unshiu Mar.) juice (MJ).
They contain high amounts of β-cryptoxanthin and hesperidin.
We have demonstrated that CHRP and/or MJs inhibit chemically induced rat colon, rat tongue, and mouse lung tumorigenesis.
Gavage with CHRP resulted in an increase of activities of detoxifying enzymes in the liver, colon, and tongue rats'.
CHRP and MJs were also able to suppress the expression of proinflammatory cytokines and inflammatory enzymes in the target tissues.
This paper describes the findings of our in vivo preclinical experiments to develop a strategy for cancer chemoprevention of colon, tongue, and lung neoplasms by use of CHRP and MJs.
American Psychological Association (APA)
Tanaka, Takuji& Tanaka, Takahiro& Tanaka, Mayu& Kuno, Toshiya. 2011. Cancer Chemoprevention by Citrus Pulp and Juices Containing High Amounts of β-Cryptoxanthin and Hesperidin. BioMed Research International،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-991750
Modern Language Association (MLA)
Tanaka, Takuji…[et al.]. Cancer Chemoprevention by Citrus Pulp and Juices Containing High Amounts of β-Cryptoxanthin and Hesperidin. BioMed Research International No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-991750
American Medical Association (AMA)
Tanaka, Takuji& Tanaka, Takahiro& Tanaka, Mayu& Kuno, Toshiya. Cancer Chemoprevention by Citrus Pulp and Juices Containing High Amounts of β-Cryptoxanthin and Hesperidin. BioMed Research International. 2011. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-991750
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991750