![](/images/graphics-bg.png)
Umbilical Cord-Derived Mesenchymal Stem Cells for Hematopoietic Stem Cell Transplantation
Joint Authors
Wu, Kang-Hsi
Peng, Ching-Tien
Chao, Yu-Hua
Tsai, Chris
Wu, Han-Ping
Chan, Chin-Kan
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-03
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Hematopoietic stem cell transplantation (HSCT) is becoming an effective therapeutic modality for a variety of diseases.
Mesenchymal stem cells (MSCs) can be used to enhance hematopoietic engraftment, accelerate lymphocyte recovery, reduce the risk of graft failure, prevent and treat graft-versus-host disease, and repair tissue damage in patients receiving HSCT.
Till now, most MSCs for human clinical application have been derived from bone marrow.
However, acquiring bone-marrow-derived MSCs involves an invasive procedure.
Umbilical cord is rich with MSCs.
Compared to bone-marrow-derived MSCs, umbilical cord-derived MSCs (UCMSCs) are easier to obtain without harm to the donor and can proliferate faster.
No severe adverse effects were noted in our previous clinical application of UCMSCs in HSCT.
Accordingly, application of UCMSCs in humans appears to be feasible and safe.
Further studies are warranted.
American Psychological Association (APA)
Chao, Yu-Hua& Wu, Han-Ping& Chan, Chin-Kan& Tsai, Chris& Peng, Ching-Tien& Wu, Kang-Hsi. 2012. Umbilical Cord-Derived Mesenchymal Stem Cells for Hematopoietic Stem Cell Transplantation. BioMed Research International،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-991885
Modern Language Association (MLA)
Chao, Yu-Hua…[et al.]. Umbilical Cord-Derived Mesenchymal Stem Cells for Hematopoietic Stem Cell Transplantation. BioMed Research International No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-991885
American Medical Association (AMA)
Chao, Yu-Hua& Wu, Han-Ping& Chan, Chin-Kan& Tsai, Chris& Peng, Ching-Tien& Wu, Kang-Hsi. Umbilical Cord-Derived Mesenchymal Stem Cells for Hematopoietic Stem Cell Transplantation. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-991885
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991885