Oral Lichen Planus as a Preneoplastic Inflammatory Model
Joint Authors
Foukas, Periklis G.
Achtari, Marina D.
Georgakopoulou, Eleni A.
Kotsinas, Athanassios
Achtaris, Michael
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Oral lichen planus (OLP) is a chronic oral inflammatory disease of unknown etiology.
According to reports, 1-2% of OLP patients develop oral squamous cell carcinoma (OSCC) in the long run.
While World Health Organization (WHO) classifies OLP as “a potentially malignant disorder,” it is still a matter of debate which mechanisms drive OLP to such a condition.
The current hypothesis connecting OLP and OSCC is that chronic inflammation results in crucial DNA damage which over time results in cancer development.
Initial studies investigating the OLP and OSCC link were mainly retrospective clinical studies.
Over the past years, several amount of information has accumulated, mainly from molecular studies on the OLP malignant potential.
This article is a critical review of whether OLP has a malignant potential and, therefore, represents a model of preneoplastic inflammation.
American Psychological Association (APA)
Georgakopoulou, Eleni A.& Achtari, Marina D.& Achtaris, Michael& Foukas, Periklis G.& Kotsinas, Athanassios. 2012. Oral Lichen Planus as a Preneoplastic Inflammatory Model. BioMed Research International،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-991886
Modern Language Association (MLA)
Georgakopoulou, Eleni A.…[et al.]. Oral Lichen Planus as a Preneoplastic Inflammatory Model. BioMed Research International No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-991886
American Medical Association (AMA)
Georgakopoulou, Eleni A.& Achtari, Marina D.& Achtaris, Michael& Foukas, Periklis G.& Kotsinas, Athanassios. Oral Lichen Planus as a Preneoplastic Inflammatory Model. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-991886
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991886