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Dermal Ultrastructure in Low Beighton Score Members of 17 Families with Hypermobile-Type Ehlers-Danlos Syndrome
Joint Authors
Delvenne, Philippe
Piérard, Gérald E.
Hermanns-Lê, Trinh
Manicourt, Daniel
Reginster, Marie-Annick
Piérard-Franchimont, Claudine
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-03
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
The distinction between the Ehlers-Danlos syndrome hypermobile type (EDSH) and the benign joint hypermobility syndrome (BJHS) is unclear.
The aim of the present study was to compare skin ultrastructural abnormalities of EDSH and BJHS among different families.
Skin of 23 EDSH, 27 BJHS, and 41 asymptomatic subjects from 17 families was examined using transmission electron microscopy.
Similar ultrastructural abnormalities were found irrespective of the Beighton score.
Flower-like collagen fibrils represented the key change and elastic fibers were altered as well.
Beighton score is a clinical parameter rating joint mobility that appeared unrelated to quantitative and qualitative collagen ultrastructural alterations in the skin.
Some EDSH family members fit with BJHS diagnosis.
BJHS possibly represents a mild variant of EDSH.
American Psychological Association (APA)
Hermanns-Lê, Trinh& Reginster, Marie-Annick& Piérard-Franchimont, Claudine& Delvenne, Philippe& Piérard, Gérald E.& Manicourt, Daniel. 2012. Dermal Ultrastructure in Low Beighton Score Members of 17 Families with Hypermobile-Type Ehlers-Danlos Syndrome. BioMed Research International،Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-991941
Modern Language Association (MLA)
Hermanns-Lê, Trinh…[et al.]. Dermal Ultrastructure in Low Beighton Score Members of 17 Families with Hypermobile-Type Ehlers-Danlos Syndrome. BioMed Research International No. 2012 (2012), pp.1-3.
https://search.emarefa.net/detail/BIM-991941
American Medical Association (AMA)
Hermanns-Lê, Trinh& Reginster, Marie-Annick& Piérard-Franchimont, Claudine& Delvenne, Philippe& Piérard, Gérald E.& Manicourt, Daniel. Dermal Ultrastructure in Low Beighton Score Members of 17 Families with Hypermobile-Type Ehlers-Danlos Syndrome. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-991941
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991941