Proteomic Analysis of Trypanosoma cruzi Epimastigotes Subjected to Heat Shock
Joint Authors
Hurtado, Gerardo
Espinoza, Bertha
Lanz-Mendoza, Humberto
Pérez-Morales, Deyanira
Martínez-Espinosa, Rodrigo
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-12
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Trypanosoma cruzi is exposed to sudden temperature changes during its life cycle.
Adaptation to these variations is crucial for parasite survival, reproduction, and transmission.
Some of these conditions may change the pattern of genetic expression of proteins involved in homeostasis in the course of stress treatment.
In the present study, the proteome of T.
cruzi epimastigotes subjected to heat shock and epimastigotes grow normally was compared by two-dimensional gel electrophoresis followed by mass spectrometry for protein identification.
Twenty-four spots differing in abundance were identified.
Of the twenty-four changed spots, nineteen showed a greater intensity and five a lower intensity relative to the control.
Several functional categories of the identified proteins were determined: metabolism, cell defense, hypothetical proteins, protein fate, protein synthesis, cellular transport, and cell cycle.
Proteins involved in the interaction with the cellular environment were also identified, and the implications of these changes are discussed.
American Psychological Association (APA)
Pérez-Morales, Deyanira& Lanz-Mendoza, Humberto& Hurtado, Gerardo& Martínez-Espinosa, Rodrigo& Espinoza, Bertha. 2012. Proteomic Analysis of Trypanosoma cruzi Epimastigotes Subjected to Heat Shock. BioMed Research International،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-991949
Modern Language Association (MLA)
Pérez-Morales, Deyanira…[et al.]. Proteomic Analysis of Trypanosoma cruzi Epimastigotes Subjected to Heat Shock. BioMed Research International No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-991949
American Medical Association (AMA)
Pérez-Morales, Deyanira& Lanz-Mendoza, Humberto& Hurtado, Gerardo& Martínez-Espinosa, Rodrigo& Espinoza, Bertha. Proteomic Analysis of Trypanosoma cruzi Epimastigotes Subjected to Heat Shock. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-991949
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991949