Engineering Airway Epithelium
Joint Authors
Soleas, John P.
Marcus, Paula
Waddell, Thomas K.
Paz, Ana
McGuigan, Alison
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-08
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Airway epithelium is constantly presented with injurious signals, yet under healthy circumstances, the epithelium maintains its innate immune barrier and mucociliary elevator function.
This suggests that airway epithelium has regenerative potential (I.
R.
Telford and C.
F.
Bridgman, 1990).
In practice, however, airway regeneration is problematic because of slow turnover and dedifferentiation of epithelium thereby hindering regeneration and increasing time necessary for full maturation and function.
Based on the anatomy and biology of the airway epithelium, a variety of tissue engineering tools available could be utilized to overcome the barriers currently seen in airway epithelial generation.
This paper describes the structure, function, and repair mechanisms in native epithelium and highlights specific and manipulatable tissue engineering signals that could be of great use in the creation of artificial airway epithelium.
American Psychological Association (APA)
Soleas, John P.& Paz, Ana& Marcus, Paula& McGuigan, Alison& Waddell, Thomas K.. 2012. Engineering Airway Epithelium. BioMed Research International،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-991984
Modern Language Association (MLA)
Soleas, John P.…[et al.]. Engineering Airway Epithelium. BioMed Research International No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-991984
American Medical Association (AMA)
Soleas, John P.& Paz, Ana& Marcus, Paula& McGuigan, Alison& Waddell, Thomas K.. Engineering Airway Epithelium. BioMed Research International. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-991984
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-991984