Brazilian Green Propolis: Anti-Inflammatory Property by an Immunomodulatory Activity
Joint Authors
Nascimento, F. R. F.
Machado, Joleen Lopes
Assunção, Anne Karine Martins
da Silva, Mayara Cristina Pinto
Reis, Aramys Silva dos
Costa, Graciomar Conceição
Arruda, Diêgo de Sousa
Rocha, Bruno Alves
Vaz, Mirela Mara de Oliveira Lima Leite
Paes, Antonio Marcus de Andrade
Guerra, Rosane Nassar Meireles
Berretta, Andresa Aparecida
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The immunomodulatory and anti-inflammatory activities of green propolis extracts from Apis mellifera were investigated using acute and chronic inflammation models.
Swiss mice were anesthetized and a cotton pellet granuloma was implanted in subcutaneous tissue.
Then the mice were divided into six groups and received apyrogenic water or different propolis extracts by oral route (5 mg/kg).
According to the treatment the groups were designated as E1A, E1B, E10, E11, and E12.
The control group received apyrogenic water.
The treatment was performed by six days when the mice were killed.
The blood and the bronchoalveolar lavage (BAL) were collected to measure the leukocyte recruitment.
In acute pulmonary inflammation, Balb/c mice received lipopolysaccharide (LPS) of Escherichia coli by intranasal route for three days.
Concomitantly the mice received by oral route apyrogenic water (control) or E10 and E11 propolis extracts.
BAL was performed to assess the inflammatory infiltrate and cytokine quantification.
The results showed that the E11 extract has anti-inflammatory property in both models by the inhibition of proinflammatory cytokines and increase of anti-inflammatory cytokines suggesting an immunomodulatory activity.
American Psychological Association (APA)
Machado, Joleen Lopes& Assunção, Anne Karine Martins& da Silva, Mayara Cristina Pinto& Reis, Aramys Silva dos& Costa, Graciomar Conceição& Arruda, Diêgo de Sousa…[et al.]. 2012. Brazilian Green Propolis: Anti-Inflammatory Property by an Immunomodulatory Activity. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-992062
Modern Language Association (MLA)
Machado, Joleen Lopes…[et al.]. Brazilian Green Propolis: Anti-Inflammatory Property by an Immunomodulatory Activity. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-992062
American Medical Association (AMA)
Machado, Joleen Lopes& Assunção, Anne Karine Martins& da Silva, Mayara Cristina Pinto& Reis, Aramys Silva dos& Costa, Graciomar Conceição& Arruda, Diêgo de Sousa…[et al.]. Brazilian Green Propolis: Anti-Inflammatory Property by an Immunomodulatory Activity. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-992062
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-992062