Cancer, Inflammation, and Insights from Ayurveda
Joint Authors
Sumantran, Venil N.
Tillu, Girish
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-04
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
A recent, exciting discovery relates to the concept of “shared pathology” between cancer and metabolic syndrome.
One major pathway common to cancer and metabolic syndrome is chronic inflammation, which is a major driving force in carcinogenesis.
Indeed, chronic inflammation precedes most cancers and is considered a “hallmark” of the neoplastic process.
We discuss molecular and biochemical evidence which links diet, obesity, abnormal lipid metabolism, and type 2 diabetes mellitus with chronic inflammation.
We also explain how each of these factors is linked with biochemical aberrations of carcinogenesis and the prevalence and risk of cancer.
While there are reliable biomarkers for chronic inflammation, there are few markers for a mechanistic link between early inflammation and digestive disorders.
Discovery of such a marker could lead to identification of a new subtype of patients with digestive disorders that predispose them to cancer and/or metabolic syndrome.
In this context, we discuss the ayurvedic concept of “Ama” which is thought to be a toxic, proinflammatory waste-product of improper digestion.
We then develop hypotheses and outline preclinical and clinical experiments designed to prove whether “Ama” can serve as a novel and reliable biomarker that links abnormal digestive status, with the onset of chronic inflammation.
American Psychological Association (APA)
Sumantran, Venil N.& Tillu, Girish. 2012. Cancer, Inflammation, and Insights from Ayurveda. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-992187
Modern Language Association (MLA)
Sumantran, Venil N.& Tillu, Girish. Cancer, Inflammation, and Insights from Ayurveda. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-992187
American Medical Association (AMA)
Sumantran, Venil N.& Tillu, Girish. Cancer, Inflammation, and Insights from Ayurveda. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-992187
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-992187