Randomized Clinical Trial on the Use of PHYSTA Freeze-Dried Water Extract of Eurycoma longifolia for the Improvement of Quality of Life and Sexual Well-Being in Men
Joint Authors
Ismail, Shaiful Bahari
Wan Mohammad, Wan Mohd Zahiruddin
George, Annie
Nik Hussain, Nik Hazlina
Musthapa Kamal, Zatul Mufiza
Liske, Eckehard
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-01
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Eurycoma longifolia is reputed as an aphrodisiac and remedy for decreased male libido.
A randomized, double-blind, placebo controlled, parallel group study was carried out to investigate the clinical evidence of E.
longifolia in men.
The 12-week study in 109 men between 30 and 55 years of age consisted of either treatment of 300 mg of water extract of E.
longifolia (Physta) or placebo.
Primary endpoints were the Quality of Life investigated by SF-36 questionnaire and Sexual Well-Being investigated by International Index of Erectile Function (IIEF) and Sexual Health Questionnaires (SHQ); Seminal Fluid Analysis (SFA), fat mass and safety profiles.
Repeated measures ANOVA analysis was used to compare changes in the endpoints.
The E.
longifolia (EL) group significantly improved in the domain Physical Functioning of SF-36, from baseline to week 12 compared to placebo (P=0.006) and in between group at week 12 (P=0.028).
The EL group showed higher scores in the overall Erectile Function domain in IIEF (P<0.001), sexual libido (14% by week 12), SFA- with sperm motility at 44.4%, and semen volume at 18.2% at the end of treatment.
Subjects with BMI ≥ 25 kg/m2 significantly improved in fat mass lost (P=0.008).
All safety parameters were comparable to placebo.
American Psychological Association (APA)
Ismail, Shaiful Bahari& Wan Mohammad, Wan Mohd Zahiruddin& George, Annie& Nik Hussain, Nik Hazlina& Musthapa Kamal, Zatul Mufiza& Liske, Eckehard. 2012. Randomized Clinical Trial on the Use of PHYSTA Freeze-Dried Water Extract of Eurycoma longifolia for the Improvement of Quality of Life and Sexual Well-Being in Men. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-992281
Modern Language Association (MLA)
Ismail, Shaiful Bahari…[et al.]. Randomized Clinical Trial on the Use of PHYSTA Freeze-Dried Water Extract of Eurycoma longifolia for the Improvement of Quality of Life and Sexual Well-Being in Men. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-992281
American Medical Association (AMA)
Ismail, Shaiful Bahari& Wan Mohammad, Wan Mohd Zahiruddin& George, Annie& Nik Hussain, Nik Hazlina& Musthapa Kamal, Zatul Mufiza& Liske, Eckehard. Randomized Clinical Trial on the Use of PHYSTA Freeze-Dried Water Extract of Eurycoma longifolia for the Improvement of Quality of Life and Sexual Well-Being in Men. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-992281
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-992281