![](/images/graphics-bg.png)
The Effects of Virgin Coconut Oil on Bone Oxidative Status in Ovariectomised Rat
Joint Authors
Shuid, Ahmad Nazrun
Ima-Nirwana, Soelaiman
Abujazia, Mouna Abdelrahman
Muhammad, Norliza
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Virgin coconut oil (VCO) was found to have antioxidant property due to its high polyphenol content.
The aim of this study was to investigate the effect of the virgin coconut oil on lipid peroxidation in the bone of an osteoporotic rat model.
Normal female Sprague-Dawley rats aged 3 months old were randomly divided into 4 groups, with 8 rats in each group: baseline, sham, ovariectomised (OVX) control group, and OVX given 8% VCO in the diet for six weeks.
The oxidative status of the bone was assessed by measuring the index of lipid peroxidation, which is malondialdehyde (MDA) concentration, as well as the endogenous antioxidant enzymes glutathione peroxidase (GPX) and superoxide dismutase (SOD) in the tibia at the end of the study.
The results showed that there was a significant decrease in MDA levels in the OVX-VCO group compared to control group.
Ovariectomised rats treated with VCO also had significantly higher GPX concentration.
The SOD level seemed to be increased in the OVX-VCO group compared to OVX-control group.
In conclusion, VCO prevented lipid peroxidation and increased the antioxidant enzymes in the osteoporotic rat model.
American Psychological Association (APA)
Abujazia, Mouna Abdelrahman& Muhammad, Norliza& Shuid, Ahmad Nazrun& Ima-Nirwana, Soelaiman. 2012. The Effects of Virgin Coconut Oil on Bone Oxidative Status in Ovariectomised Rat. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-992387
Modern Language Association (MLA)
Abujazia, Mouna Abdelrahman…[et al.]. The Effects of Virgin Coconut Oil on Bone Oxidative Status in Ovariectomised Rat. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-992387
American Medical Association (AMA)
Abujazia, Mouna Abdelrahman& Muhammad, Norliza& Shuid, Ahmad Nazrun& Ima-Nirwana, Soelaiman. The Effects of Virgin Coconut Oil on Bone Oxidative Status in Ovariectomised Rat. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-992387
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-992387