![](/images/graphics-bg.png)
A Systematic Review of Xuezhikang, an Extract from Red Yeast Rice, for Coronary Heart Disease Complicated by Dyslipidemia
Joint Authors
Xu, Hao
Liu, Jian-Ping
Shang, Qing-hua
Liu, Zhaolan
Chen, Ke-Ji
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-12
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
This systematic review aims to evaluate the benefit and side effect of Xuezhikang for coronary heart disease (CHD) complicated by dyslipidemia.
Methods.
All randomized clinical trials (RCTs) with Xuezhikang as a treatment for CHD combined with dyslipidemia were considered for inclusion.
Data extraction and analyses and quality assessment were conducted according to the Cochrane standards.
Results.
We included 22 randomized trials.
Xuezhikang showed significant benefit on the incidence of all-cause deaths, CHD deaths, myocardial infarction, and revascularization as compared with placebo based on conventional treatment for CHD.
It remarkably lowered total cholesterol (TC), triglyceride (TG), and low-density lipoprotein-cholesterol (LDL-C) as compared with the placebo or inositol nicotinate group, which was similar to statins group.
Xuezhikang also raised high-density lipoprotein cholesterol (HDL-C) compared to placebo or no intervention, which was similar to Inositol nicotinate and slightly inferior to statins.
The incidence of adverse events did not differ between the Xuezhikang and control group.
Conclusions.
Xuezhikang showed a comprehensive lipid-regulating effect and was safe and effective in reducing cardiovascular events in CHD patients complicated by dyslipidemia.
However, more rigorous trials with high quality are needed to give high level of evidence.
American Psychological Association (APA)
Shang, Qing-hua& Liu, Zhaolan& Chen, Ke-Ji& Xu, Hao& Liu, Jian-Ping. 2012. A Systematic Review of Xuezhikang, an Extract from Red Yeast Rice, for Coronary Heart Disease Complicated by Dyslipidemia. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-18.
https://search.emarefa.net/detail/BIM-992484
Modern Language Association (MLA)
Shang, Qing-hua…[et al.]. A Systematic Review of Xuezhikang, an Extract from Red Yeast Rice, for Coronary Heart Disease Complicated by Dyslipidemia. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-18.
https://search.emarefa.net/detail/BIM-992484
American Medical Association (AMA)
Shang, Qing-hua& Liu, Zhaolan& Chen, Ke-Ji& Xu, Hao& Liu, Jian-Ping. A Systematic Review of Xuezhikang, an Extract from Red Yeast Rice, for Coronary Heart Disease Complicated by Dyslipidemia. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-18.
https://search.emarefa.net/detail/BIM-992484
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-992484