Evaluation of the Acetone and Aqueous Extracts of Mature Stem Bark of Sclerocarya birrea for Antioxidant and Antimicrobial Properties
Joint Authors
Tanih, Nicoline F.
Ndip, Roland N.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-17
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We assayed the antimicrobial activity of acetone and aqueous extracts of the stem bark of Sclerocarya birrea on some selected bacteria and fungi species including; Streptococcus pyogenes, Plesiomonas shigelloides, Aeromonas hydrophila, Salmonella typhimurium, Cryptococcus neoformans, Candida glabrata, Trichosporon mucoides, and Candida krusei using both agar well diffusion and minimum inhibitory concentration (MIC) assays.
Based on the levels of activity, the acetone extract was examined for total polyphenolic content, radical scavenging and antioxidant activities.
Total phenols of the extract were determined spectrophotometrically.
The antioxidant activity was determined by the DPPH, ABTS and reducing power.
All the bacteria and fungi species were susceptible to the plant extracts.
The acetone extract was the most active for the bacterial species with MIC (0.156–0.625 mg/mL) while the aqueous extract was the most active for the fungi species with MIC (0.3125–1.25 mg/mL).
The polyphenolic compounds were found as 27.2 mg/g tannic acid equivalent, 25.2 mg/g quercetin equivalent, 9.1 mg/g quercetin equivalent for phenols, flavonoid and flavonols respectively.
The acetone extract exhibited a remarkable ability to scavenge radicals, strong reducing ability and a potential source of natural antioxidants.
Both the acetone and aqueous extracts of S.
birrea may provide a target for drug discovery.
American Psychological Association (APA)
Tanih, Nicoline F.& Ndip, Roland N.. 2012. Evaluation of the Acetone and Aqueous Extracts of Mature Stem Bark of Sclerocarya birrea for Antioxidant and Antimicrobial Properties. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-992691
Modern Language Association (MLA)
Tanih, Nicoline F.& Ndip, Roland N.. Evaluation of the Acetone and Aqueous Extracts of Mature Stem Bark of Sclerocarya birrea for Antioxidant and Antimicrobial Properties. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-992691
American Medical Association (AMA)
Tanih, Nicoline F.& Ndip, Roland N.. Evaluation of the Acetone and Aqueous Extracts of Mature Stem Bark of Sclerocarya birrea for Antioxidant and Antimicrobial Properties. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-992691
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-992691