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Antiatherosclerotic Effect of Canarium odontophyllum Miq. Fruit Parts in Rabbits Fed High Cholesterol Diet
Joint Authors
Azlan, Azrina
Shakirin, Faridah Hanim
Ismail, Amin
Cheng Yuon, Lau
Amom, Zulkhairi
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-16
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The effect of C.
odontophyllum (CO) fruit parts was investigated in hypercholesterolemic rabbits.
Forty-nine rabbits, which were randomly divided into seven groups of seven animals (n=7), received a diet containing different parts of CO fruit parts for 8 weeks.
The groups were as follows: (1) normal diet: NC group and (2) hypercholesterolemic diet: PC, HS (10 mg/kg/day simvastatin), HPO (20 g kg−1 oil extracted from the pulp of CO), HKO (20 g kg−1 oil extracted from the kernel of CO), HF (50 g kg−1 fullfat pulp of CO), and HD (50 g kg−1 defatted pulp of CO).
Among these groups, rabbits receiving defatted pulp of CO showed the greatest cholesterol lowering effect as it had reduced plasma LDL-C, TC, and thiobarbiturate reactive substance (TBARS) levels as well as atherosclerotic plaques.
The presence of high dietary fiber and antioxidants activity are potential factors contributing to the cholesterol lowering effect.
Consequently, these results indicate the potential use of CO defatted pulp as a cholesterol lowering and antioxidant agent.
American Psychological Association (APA)
Shakirin, Faridah Hanim& Azlan, Azrina& Ismail, Amin& Amom, Zulkhairi& Cheng Yuon, Lau. 2012. Antiatherosclerotic Effect of Canarium odontophyllum Miq. Fruit Parts in Rabbits Fed High Cholesterol Diet. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-992700
Modern Language Association (MLA)
Shakirin, Faridah Hanim…[et al.]. Antiatherosclerotic Effect of Canarium odontophyllum Miq. Fruit Parts in Rabbits Fed High Cholesterol Diet. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-992700
American Medical Association (AMA)
Shakirin, Faridah Hanim& Azlan, Azrina& Ismail, Amin& Amom, Zulkhairi& Cheng Yuon, Lau. Antiatherosclerotic Effect of Canarium odontophyllum Miq. Fruit Parts in Rabbits Fed High Cholesterol Diet. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-992700
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-992700