Prevalence and Risk Factors of Prolonged QTc Interval among Chinese Patients with Type 2 Diabetes
Joint Authors
Liu, Yan-jun
Li, Xiang
Liu, Jian-qin
Xu, Zhang-rong
Yang, Xiao-pin
Ren, Hui
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-25
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
|Objectives.
The aim of this study was to evaluate the prevalence and the risk factors of prolonged QTc interval among Chinese patients with type 2 diabetes.
Methods.
The retrospective study included 3156 outpatients from the Diabetes Centre, the 306th Hospital of PLA, during the period from September 2003 to June 2010.
QT interval was measured manually in the 12-lead conventional electrocardiogram.
The QT interval corrected for heart rate (QTc) was calculated using Bazett’s formula.
Additional demographic and laboratory data were also collected.
Potential risk factors of prolonged QTc interval were assessed using multivariable regression.
Results.
The prevalence of prolonged QTc interval among Chinese patients with type 2 diabetes was 30.1%.
Height (OR 0.156, 95% CI 0.032~0.748), waist circumference (OR 1.025, 95% CI 1.010~1.040), diastolic blood pressure (OR 1.016, 95% CI 1.007~1.026), postprandial glucose (OR 1.040, 95% CI 1.022~1.059), fasting insulin (OR 1.014, 95% CI 1.003~1.025), and presence of microalbuminuria (OR 1.266, 95% CI 1.033~1.551) were significant risk factors.
Conclusions.
The prevalence of prolonged QTc interval among Chinese patients with type 2 diabetes is high.
Risk factors for prolongation of QTc interval were low height, high waist circumference, increasing diastolic blood pressure levels, high postprandial glucose levels, high fasting insulin levels, and presence of microalbuminuria.
American Psychological Association (APA)
Li, Xiang& Ren, Hui& Xu, Zhang-rong& Liu, Yan-jun& Yang, Xiao-pin& Liu, Jian-qin. 2012. Prevalence and Risk Factors of Prolonged QTc Interval among Chinese Patients with Type 2 Diabetes. Journal of Diabetes Research،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-993942
Modern Language Association (MLA)
Li, Xiang…[et al.]. Prevalence and Risk Factors of Prolonged QTc Interval among Chinese Patients with Type 2 Diabetes. Journal of Diabetes Research Vol. 2012, no. 2012 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-993942
American Medical Association (AMA)
Li, Xiang& Ren, Hui& Xu, Zhang-rong& Liu, Yan-jun& Yang, Xiao-pin& Liu, Jian-qin. Prevalence and Risk Factors of Prolonged QTc Interval among Chinese Patients with Type 2 Diabetes. Journal of Diabetes Research. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-993942
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-993942