Autophagy as a Therapeutic Target in Diabetic Nephropathy
Joint Authors
Maegawa, Hiroshi
Kanasaki, Keizo
Kitada, Munehiro
Uzu, Takashi
Tanaka, Yuki
Kume, Shinji
Koya, Daisuke
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2011), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-19
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Diabetic nephropathy is a serious complication of diabetes mellitus, and its prevalence has been increasing worldwide.
Therefore, there is an urgent need to identify a new therapeutic target to prevent diabetic nephropathy.
Autophagy is a major catabolic pathway involved in degrading and recycling macromolecules and damaged organelles to maintain intracellular homeostasis.
The study of autophagy in mammalian systems is advancing rapidly and has revealed that it is involved in the pathogenesis of various metabolic or age-related diseases.
The functional role of autophagy in the kidneys is also currently under intense investigation although, until recently, evidence showing the involvement of autophagy in the pathogenesis of diabetic nephropathy has been limited.
We provide a systematic review of autophagy and discuss the therapeutic potential of autophagy in diabetic nephropathy to help future investigations in this field.
American Psychological Association (APA)
Tanaka, Yuki& Kume, Shinji& Kitada, Munehiro& Kanasaki, Keizo& Uzu, Takashi& Maegawa, Hiroshi…[et al.]. 2011. Autophagy as a Therapeutic Target in Diabetic Nephropathy. Journal of Diabetes Research،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-994034
Modern Language Association (MLA)
Tanaka, Yuki…[et al.]. Autophagy as a Therapeutic Target in Diabetic Nephropathy. Journal of Diabetes Research Vol. 2012, no. 2012 (2011), pp.1-12.
https://search.emarefa.net/detail/BIM-994034
American Medical Association (AMA)
Tanaka, Yuki& Kume, Shinji& Kitada, Munehiro& Kanasaki, Keizo& Uzu, Takashi& Maegawa, Hiroshi…[et al.]. Autophagy as a Therapeutic Target in Diabetic Nephropathy. Journal of Diabetes Research. 2011. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-994034
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-994034