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Gender Differences in the Pathogenesis and Outcome of Lupus and of Lupus Nephritis
Joint Authors
Putterman, Chaim
Schwartzman-Morris, Julie
Source
Journal of Immunology Research
Issue
Vol. 2012, Issue 2012 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Systemic Lupus Erythematosus (SLE) typically affects females at far greater rates than males; however male SLE patients often have more severe disease than females.
The gender disparities have been reported in clinical manifestations and in serological and hematological indices as well.
In particular, SLE complicated with nephritis is more frequent in men than women, and several groups identified male gender as a risk factor for progression to renal failure.
The specific differences in pathogenesis amongst genders have yet to be conclusively defined, though genetic, hormonal, and immune responses have been analyzed thus far.
Further research is warranted to further elucidate these differences and permit the development of gender-tailored treatment regimens.
American Psychological Association (APA)
Schwartzman-Morris, Julie& Putterman, Chaim. 2012. Gender Differences in the Pathogenesis and Outcome of Lupus and of Lupus Nephritis. Journal of Immunology Research،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-994533
Modern Language Association (MLA)
Schwartzman-Morris, Julie& Putterman, Chaim. Gender Differences in the Pathogenesis and Outcome of Lupus and of Lupus Nephritis. Journal of Immunology Research Vol. 2012, no. 2012 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-994533
American Medical Association (AMA)
Schwartzman-Morris, Julie& Putterman, Chaim. Gender Differences in the Pathogenesis and Outcome of Lupus and of Lupus Nephritis. Journal of Immunology Research. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-994533
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-994533