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Recent Understanding on Diagnosis and Management of Central Nervous System Vasculitis in Children
Joint Authors
Del Balzo, Francesca
Iannetti, Ludovico
Ulgiati, Fiorenza
Bruschi, Simone
Nicita, Francesco
Zito, Roberta
Papetti, Laura
Spalice, Alberto
Source
Journal of Immunology Research
Issue
Vol. 2012, Issue 2012 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-12
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Central nervous system vasculitides in children may develop as a primary condition or secondary to an underlying systemic disease.
Many vasculitides affect both adults and children, while some others occur almost exclusively in childhood.
Patients usually present with systemic symptoms with single or multiorgan dysfunction.
The involvement of central nervous system in childhood is not frequent and it occurs more often as a feature of subtypes like childhood polyarteritis nodosa, Kawasaki disease, Henoch Schönlein purpura, and Bechet disease.
Primary angiitis of the central nervous system of childhood is a reversible cause of severe neurological impairment, including acute ischemic stroke, intractable seizures, and cognitive decline.
The first line therapy of CNS vasculitides is mainly based on corticosteroids and immunosuppressor drugs.
Other strategies include plasmapheresis, immunoglobulins, and biologic drugs.
This paper discusses on current understanding of most frequent primary and secondary central nervous system vasculitides in children including a tailored-diagnostic approach and new evidence regarding treatment.
American Psychological Association (APA)
Iannetti, Ludovico& Zito, Roberta& Bruschi, Simone& Papetti, Laura& Ulgiati, Fiorenza& Nicita, Francesco…[et al.]. 2012. Recent Understanding on Diagnosis and Management of Central Nervous System Vasculitis in Children. Journal of Immunology Research،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-996792
Modern Language Association (MLA)
Iannetti, Ludovico…[et al.]. Recent Understanding on Diagnosis and Management of Central Nervous System Vasculitis in Children. Journal of Immunology Research Vol. 2012, no. 2012 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-996792
American Medical Association (AMA)
Iannetti, Ludovico& Zito, Roberta& Bruschi, Simone& Papetti, Laura& Ulgiati, Fiorenza& Nicita, Francesco…[et al.]. Recent Understanding on Diagnosis and Management of Central Nervous System Vasculitis in Children. Journal of Immunology Research. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-996792
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-996792