Autoantibodies to Apolipoprotein A-1 in Cardiovascular Diseases: Current Perspectives
Joint Authors
Cutler, P.
Teixeira, P. C.
Vuilleumier, N.
Source
Journal of Immunology Research
Issue
Vol. 2012, Issue 2012 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-20
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Immune-mediated inflammation plays a major role in atherosclerosis and atherothrombosis, two essential features for cardiovascular disease (CVD) development, currently considered as the leading cause of death in the western world.
There is accumulating evidence showing that humoral autoimmunity might play an important role in CVD and that some autoantibodies could represent emerging cardiovascular risk factors.
Recent studies demonstrate that IgG autoantibodies against apolipoprotein A-1 (apoA-1) are raised in many diseases associated with a high cardiovascular risk, such as systemic lupus erythematosus, acute coronary syndrome, rheumatoid arthritis, severe carotid stenosis, and end-stage renal disease.
In this work, we aimed at reviewing current data in the literature pointing to anti-apolipoprotein A-1 antibodies (anti-apoA-1 IgG) as a possible prognostic and diagnostic biomarker of cardiovascular risk and appraising their potential role as active mediators of atherogenesis.
American Psychological Association (APA)
Teixeira, P. C.& Cutler, P.& Vuilleumier, N.. 2012. Autoantibodies to Apolipoprotein A-1 in Cardiovascular Diseases: Current Perspectives. Journal of Immunology Research،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-996900
Modern Language Association (MLA)
Teixeira, P. C.…[et al.]. Autoantibodies to Apolipoprotein A-1 in Cardiovascular Diseases: Current Perspectives. Journal of Immunology Research Vol. 2012, no. 2012 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-996900
American Medical Association (AMA)
Teixeira, P. C.& Cutler, P.& Vuilleumier, N.. Autoantibodies to Apolipoprotein A-1 in Cardiovascular Diseases: Current Perspectives. Journal of Immunology Research. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-996900
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-996900